One of the biggest challenges in cancer treatment is chemoresistance: Tumors that initially respond well to chemotherapy ...
Niraparib significantly improved PFS and time without symptoms for women with advanced ovarian cancer who responded to ...
Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women's Health Initiative Randomized Trials Cancers with homologous recombination deficiency (HRD) can ...
Tokyo, Japan – Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a ...
The combination of niraparib and abiraterone halves the spread of prostate cancer in men with BRCA gene mutations.
Myriad Genetics (($MYGN)) announced an update on their ongoing clinical study. Myriad Genetics (MYGN) is collaborating on a clinical study titled ...
Poly ADP-ribose polymerase inhibitors (PARPi) are used for patients with advanced prostate cancer bearing alterations in homologous recombination repair (HRR) genes. We sought to characterize HRR gene ...
Homologous recombination (HR) is an important process that plays multiple crucial roles during meiosis, a type of cell cycle dedicated to sexual reproduction. During HR, homologous DNA molecules ...
A study reveals the secrets behind the rodent’s remarkable ability to live 10 times longer than expected, without cancer or ...
A recent study, undertaken by researchers at the Tokyo Metropolitan University and the Tokyo Metropolitan Institute of Medical Science (both Japan), unravels key steps in the process of homologous ...
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