Background SIRT6 acts as a tumour suppressor in multiple cancers by regulating glucose and lipid metabolism, but its role in ...

Several seminal studies published in Gut have demonstrated a strong association between dysfunctional sucrase-isomaltase (SI) ...

Early broadly neutralising antibody responses against the E1E2 glycoprotein seem to be important for preventing persistence ...

Endoscopic submucosal dissection (ESD) enables en bloc resection for early gastrointestinal malignancies but is technically ...

Background Gastric cancer (GC) ranks among the most prevalent lethal tumours globally. Cancer-associated fibroblasts (CAFs) are pivotal in creating an immunosuppressive tumour microenvironment (TME) ...

We thank Drs Fujisawa and Fujikawa for their thoughtful comments, which highlight professional and organisational determinants that complement our data on waste generation.1 2 In our multicentre study ...

Objective Tryptophan can be catabolised to various metabolites through host kynurenine and microbial indole pathways. We aimed to examine relationships of host and microbial tryptophan metabolites ...

Background Covid-19 Induced Hepatitis (CIH), is a novel terminology which is used in this article for the first time in the medical literature. Objective To study the pattern of liver impairment in ...

Dr A Fasano, Division of Pediatric Gastroenterology and Nutrition, University of Maryland School of Medicine, 685 W Baltimore St HSF Building, Room 465, Baltimore, MD 21201, USA.

Background Existing scales for assessing faecal incontinence have not been validated against clinical assessment, or with regard to reproducibility. They also fail to take into account faecal urgency, ...

Objective Hepatitis D virus (HDV) is a defective virus that completes its life cycle only with hepatitis B virus (HBV). The HBV with HDV super-infection has been considered as one of the most severe ...

Section of Digestive Diseases and Nutrition, University of Illinois at Chicago and Chicago Veterans Administration Medical Center (West Side Division), Chicago, IL, USA Correspondence to: Dr G Hecht, ...