Unlocking cell identity: RNA sequestration in P-bodies directs cell fate transitions

A new study published in Nature Biotechnology shows that stem cell differentiation is linked to cellular structures called ...

Matching gene expression to metabolite production in single plant cells

A research team at the Max Planck Institute for Chemical Ecology has successfully combined single-cell RNA sequencing (scRNA-seq) and single-cell mass spectrometry (scMS) analysis on the same plant ...
C&EN

Enhanced RNA Preservation in Mouse Brain Tissue: A Strategy Combining Cardiac Perfusion with Hypersaline Immersion

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. One of the key research methods for low-density spatial transcriptomics involves ...
IEEE

kmmDE: a Non-parametric Method for Differential Expression Analysis of Time-course RNA-seq Data Using Maximum Mean Discrepancy

Abstract: Accurately identifying differentially expressed genes from time-course RNA-Seq data is essential for understanding the dynamics of transcriptome changes during biological processes. Although ...
BioSpace

Baylor Genetics to Showcase RNA Sequencing Breakthroughs for Rare Disease Diagnosis at 2025 AGBT Precision Health Meeting

HOUSTON, Aug. 25, 2025 (GLOBE NEWSWIRE) -- Baylor Genetics, a clinical diagnostic laboratory at the forefront of genetic testing, today announced its participation in the 2025 Advances in Genome ...
C&EN

Genome-Wide Identification of Microglia-Related RNA-Binding Proteins and Regulated Alternative Splicing in Spinal Cord Injury

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. The present study aimed to investigate the potential ...
EurekAlert!

Single-cell RNA sequencing reveals Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131–TNF signaling pathway-mediated differentiation of ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the ...
IEEE

Surrogate-Assisted Multiobjective Gene Selection for Cell Classification From Large-Scale Single-Cell RNA Sequencing Data

Abstract: Accurate cell classification is crucial but expensive for large-scale single-cell RNA sequencing (scRNA-seq) analysis. Gene selection (GS) emerges as a pivotal technique in identifying gene ...
Neuroscience News

Exercise Rewires Alzheimer’s-Affected Brain Cells

Summary: Using cutting-edge RNA sequencing, researchers mapped how exercise affects specific brain cell types in a model of Alzheimer’s disease. They found that physical activity alters gene activity ...
Frontiers

Integrative single-cell and cell-free plasma RNA transcriptomics identifies biomarkers for early non-invasive AD screening

1 State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan, China 2 Yunnan Key Laboratory of ...
ascopubs.org

Combining abemaciclib, temozolomide, and radiation in DIPG PDOX models: Insights from single-cell RNA-seq on cellular subtypes and genes critical for responsiveness and resistance.

Development and validation of a droplet digital PCR (ddPCR) assay to detect MGMT promoter methylation in FFPE tumors of glioblastoma (GBM) patients. This is an ASCO Meeting Abstract from the 2025 ASCO ...