Mismatch Repair Deficiency Market Forecasts Strong Expansion During the Forecast Period (2025-2034) Driven by Rising Diagnostics and Immuno-Oncology Advances | DelveInsight

DelveInsight's Mismatch Repair Deficiency Market Insights report includes a comprehensive understanding of current treatment practices, mismatch repair deficiency emerging drugs, market share of ...

Microsoft’s Emergency Fix Restores Windows 11 Recovery

The urgent fix addresses a dangerous flaw that disabled USB keyboards and mice in recovery mode, exactly when users need them ...
Targeted Oncology

FDA Grants Fast Track to NG-350A for pMMR Rectal Cancer

FDA fast track designation for NG-350A aims to expedite its development for mismatch repair-proficient locally advanced ...
CURE

FDA Fast Tracks NG-350A for Some With Advanced Rectal Cancer

NG-350A has received FDA fast track designation for mismatch repair-proficient locally advanced rectal cancer, addressing a significant unmet medical need. The drug is an intravenously delivered ...
Frontiers

Clinicopathological characteristics and loss of mismatch repair protein expression in Chinese upper tract urothelial carcinomas

Expression of DNA mismatch repair (MMR) protein (MLH1, PMS2, MSH2, and MSH6) in upper tract urothelial carcinoma (UTUC) has been explored in Western cohorts, but it is rarely reported in Eastern ...
Targeted Oncology

FDA Approves New Companion Dx, Advancing Precision in Colorectal Cancer

The FDA approves Agilent's MMR IHC Panel, enhancing personalized colorectal cancer treatment by identifying patients for targeted immunotherapy options. In a step for personalized cancer care, the US ...
C&EN

Tricyclic and Novel Chemotypes as Selective WRN Helicase Inhibitors for MSI-H Cancer Therapy

Recent advances targeting WRN helicase highlight a promising synthetic lethality approach for treating microsatellite instability-high (MSI-H) cancers. GlaxoSmithKline and Moma Therapeutics ...
Medscape

Mismatch Repair Status Linked to Endometrial Cancer Outcomes, Real-World Study Reveals

A retrospective study found that patients with mismatch repair (MMR)-deficient advanced or recurrent endometrial cancer had numerically longer overall survival (OS) than those with MMR-proficient ...
Oncology Nurse Advisor

Mismatch Repair Germline Pathogenic Variants Could Predispose to Uveal Melanoma

Twenty-one pathogenic variants found in clinically relevant genes, with an enrichment in mismatch repair genes. HealthDay News — Mismatch repair (MMR) germline alterations are enriched among patients ...
dermatologyadvisor

Mismatch Repair Germline Pathogenic Variants Could Predispose to Uveal Melanoma

21 of 79 pathogenic variants of uveal melanoma exhibited an enrichment in mismatch repair genes. HealthDay News — Mismatch repair (MMR) germline alterations are enriched among patients with uveal ...
Frontiers

A brief review of Lynch syndrome: understanding the dual cancer risk between endometrial and colorectal cancer

1 Medical Biotechnology Lab, Faculty of Allied Health Sciences, Chettinad Academy of Research and Education (CARE), Chettinad Hospital and Research Institute (CHRI), Chennai, India 2 Department of ...