Cell transformation is associated with anchorage independent growth and morphological changes characterized by reduced adhesion and spreading. The molecular signals that control these events are ...

The cells with electrophysiological activity obtained at the University of the Basque Country (UPV/EHU) are opening up new avenues for the study of neurodegenerative diseases and the development of ...

A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become ...

Gardner’s team first focused their efforts on the challenging task of creating mouse strains that could recapitulate the complex transformation in a simplified model. “It took three years to make ...

Imagine watching an embryo form in real time, each cell dividing, moving, and finding its place. Today’s advanced microscopes can capture these frames—but turning them into accurate, usable maps of ...

“Allogeneic transplants can be very effective, and potentially lifesaving, but not all immune cells given to a recipient are reproduced from donor cells,” said Jonathan Serody, MD. “Innate type 2 ...

Membrane fusion and budding mediate fundamental biological processes like intracellular trafficking, exocytosis, and endocytosis. For many decades, fusion has been thought to open a nanometer-range ...

Two American biologists have won this year's Nobel Prize in Physiology or Medicine for discovering a crucial way genes are regulated. Two American biologists have won this year's Nobel Prize in ...

Around the same time, Mack Fulwyler, an engineer working at Los Alamos National Laboratory, needed to separate particles, so he drew on existing techniques to create droplets to separate cells from a ...