Cell transformation is associated with anchorage independent growth and morphological changes characterized by reduced adhesion and spreading. The molecular signals that control these events are ...

M Miriam Merad’s fascination with macrophages began when she looked into the lungs of a cancer patient she’d just lost during ...

The cells with electrophysiological activity obtained at the University of the Basque Country (UPV/EHU) are opening up new avenues for the study of neurodegenerative diseases and the development of ...

A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become ...

Imagine watching an embryo form in real time, each cell dividing, moving, and finding its place. Today’s advanced microscopes can capture these frames—but turning them into accurate, usable maps of ...

Gardner’s team first focused their efforts on the challenging task of creating mouse strains that could recapitulate the complex transformation in a simplified model. “It took three years to make ...

New plate-based multiplexing unlocks ultra high-sample and cell-throughput single cell analysis to empower a broad range of ...

Membrane fusion and budding mediate fundamental biological processes like intracellular trafficking, exocytosis, and endocytosis. For many decades, fusion has been thought to open a nanometer-range ...